Find information about common, infrequent and rare side effects of Theophylline Oral. If they do not, or your pet has a rapid heartbeat, or an increase in appetite, drinking or urination, contact your veterinarian. Theophylline is used off label to treat cough caused by bronchoconstriction. This drug should only be given to the animal for which it was prescribed. Possible side effects include anxiety, nervousness and gastrointestinal problems. Theophylline is appropriate for use on cats and dogs when it is administered under the guidance of a veterinarian. Side-effects, further information. However, the patient can still experience side effects with this drug. Plasma-potassium concentration should therefore be monitored in severe asthma. Learn more about Theophylline … Kidney problems 5. Many of the milder side-effects occur at the start of therapy but will resolve over time. Humans are sensitive to these side effects … If you suspect your pet or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A. Sometimes theophylline is used in addition to other medications to achieve or improve symptom management. 405 HERON DRIVE SUITE 200 • SWEDESBORO, NJ 08085-1749 | © 2004-2017 WEDGEWOOD PHARMACY, ALL RIGHTS RESERVED. Ordering compounded medications is easier than ever. It is highly recommended not to administer this drug to your cat if he or she suffers from: 1. Less-common but more-serious side effects include abnormal heart rhythm and seizures. Other potential adverse effects include nausea, vomiting, and diarrhea. Theophylline works by relaxing the smooth muscles of the airway… Theophylline is safe for use on cats and dogs when it is administered under the guidance of a veterinarian. It is also available as a 80 mg/15 ml or 150 mg/15 ml syrup. Dr. Evan Ware is a veterinary practitioner in Phoenix, Arizona. Theophylline and aminophylline: theophylline toxicity. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Theophylline is very effective at relaxing the muscles surrounding the airway and clearing out the mucus that can make breathing more difficult. When administering Theophylline in tablet form, the tablet needs to be swallowed whole, not chewed. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with theophylline. Theophylline is available in a range of formulations, including tablet, capsule, and oral liquid. Theophylline has been used as an adjunct treatment in heart failure. All Rights Reserved. Be certain to complete the prescription unless specifically directed by your veterinarian. Heart disease 3. Adverse Effects [please contact CVCA should any of these symptoms be noted] Caffeine like side effects (anxiety, restlessness, panting) Decreased appetite, vomiting or diarrhea; Increased heart rate and risk for arrhythmias; Small increased risk for … … The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. The dosage and administration of Theophylline varies according to the size and breed of the pet being treated, and the type and severity of their illness, but typically, the drug is taken every 6, 8, 12, or 24 hours. The effects of theophylline on psychomotor functioning and school performance have been examined and have generally shown no significant negative on learning or behavior. It can also be given intravenously (into a vein) for treatment for severe asthma attacks or COPD exacerbations. 4. This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug. It is also related to the drug aminophylline and oxtriphylline. For cats, theophylline is dosed at 2 mg per pound (4 mg/kg) one to three times daily. High blood pressure 4. It should be used with caution in pets with abnormal heart rhythms, seizures, stomach ulcers, hyperthyroidism, kidney, liver, or heart disease, severely high blood pressure, severely low blood oxygen levels, … Theophylline is available in both an oral and an injectable form. Very young and very old animals may metabolize this drug more slowly. May cause seizures at high doses. Particular caution is required in severe asthma, because this effect may be potentiated by concomitant treatment with theophylline and its derivatives, corticosteroids, and diuretics, and by hypoxia. The drug should not be prescribed to pregnant or lactating patients or horses. Stop giving theophylline and call your veterinarian at once if any of the following side effects occur seizures severe nausea and vomiting, and restlessness coughing up blood or vomit that looks like coffee grounds urinating more than normal. Theophylline can be used with corticosteroids and may allow using a lower dose of the corticosteroid. Shipping Carrier Delays Expected - We have been advised by our carriers that packages may require 2 or more additional days for standard delivery, because of the Corona Virus. Seizures can occur if the animal receives a significant overdose. Most commonly, the side effects of Theophylline include central nervous system excitement, vomiting, fever, rash, and heart palpitations. It is very well-absorbed after oral administration. Pimobendan (Vetmedin) is a heart medication that is becoming a frequently used drug for dogs with heart disease. Lidocaine: enhanced GI and neurologic side effects. Wedgewood Pharmacy’s compounded veterinary preparations are not intended for use in food and food-producing animals. Some clinicians will start an animal on a lower dose and increase the theophylline to the therapeutic dose after the first week. Dr. Ware is currently the Medical Director of University Animal Hospital (VCA) and is also the owner of two other hospitals, including Laveen Veterinary Center and Phoenix Veterinary Center. However, if the patient experiences prolonged vomiting or diarrhea, or she develops hives or other signs of an allergic reaction, then she should be taken to the veterinarian as soon as possible. … Theophylline Side Effects Theophylline is a bronchodilator, which a veterinarian may prescribe for your pooch to help relax her airways. Other potential adverse effects include nausea, vomiting, and diarrhea. Due to the way this drug is metabolized, the dose for your pet will be calculated based on their ideal or lean body weight. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. Other side effects that are likely to occur are vomiting, diarrhea, increased palpitation, a rise in body temperature, increased heart rate, skin rashes etc. Isa and others published Effect Of Theophylline On Blood Pressure Of Normotensive Cats Pre-Administered With Adrenaline | Find, read and cite all … The medication has certain side effects such as irritation in the stomach, nervous system excitement etc. The drug should be used with caution in animals with liver or heart disease. Potentially serious hypokalaemia may result from beta 2-agonist therapy. Make sure that your cat does not eat fatty meals while taking Theophylline. Body Language of Cats . It helps clear out mucus build-up by increasing the movement of cilia within the airway. Theophylline is considered a component of a treatment plan. Winter Holiday Hazards for Pets. Theophylline, also known as Theo-Dur®, belongs to the class of drugs known as smooth muscle relaxants, affecting the respiratory muscles in dogs and cats. If any of the following serious side effects occur, stop giving Theophylline ER and seek emergency veterinary medical attention: an allergic reaction such as difficulty breathing, swelling of the lips, tongue, face, or hives. PDF | On Jan 1, 2014, A.I. ©Copyright 1999 - 2021. Theophylline. Human formulations: Theo-Dur® (Key Pharmaceuticals) and various generic brands are available. There are a number of other possible drug interactions with theophylline, including: Allopurinal, beta-blockers, propanolol, cimetidine, calcium channel blockers, corticosteroids, thiabendazole, exogenous thyroid hormone, macrolide antibiotics, flouroquinolones antibiotics, barbiturates, rifampin, carbamazine, charcoal, phenytoin, ketoconazole, beta-agonists, lithium, pancuronium, propofol, isoniazid, furosemide, ephedrine, isoproterenol, halothane, and ketamine. Discussion Guide for Pet Owners and Veterinarians, Medication Information for Pet and Horse Owners. Each of these drugs is properly called a methylxanthine. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance. Theophylline should not be used in animals with known hypersensitivity or allergy to the drug. Ordering your pet's prescription drugs from Wedgewood Pharmacy is safe, and convenient. Be sure to discuss any side-effects with your veterinarian immediately. Find everything you need to know about Theophylline (Theo-24), including what it is used for, warnings, reviews, side effects, and interactions. Beta blockers improve cardiac performance indirectly by reducing the heart rate; prolonging diastole, which allows more time for ventricular and coronary arterial filling. Cats: 2 mg/lb every 8-12 hours. This drug is registered for use in humans only. Methylxanthine drugs, such as theophylline, work by inhibiting enzymes (phosphodiesterases) inside of cells and promoting dilation of smooth muscle in bronchial tubes and blood vessels. Wash your hands after giving your pet this medication. While generally safe and effective when prescribed by a veterinarian, theophylline can cause side effects in some animals. Do not double dose to catch up. The negative side effects of theophylline include: restlessness or caffeine-type jitters (this can be minimized by starting the medication at a lower dose and gradually increasing to the recommended dose), diuretic effect (some individuals only), upset stomach, racing heart rate with abnormal heart rhythm (also only some individuals). Theophylline also works to strengthen the patient's diaphragm, and this is integral in improving the patient's ability to breathe. Do not give this medication to a person. Theophylline is used in feline asthma and in chronic bronchitis in dogs. In most cases, the side effects can be managed through … These side effects usually disappear after a short time. The … Theophylline is appropriate for use on cats and dogs when it is administered under the guidance of a veterinarian. If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222. Give theophylline on an empty stomach, 1 hour before or 2 hours after a meal. 4 Theophylline is … It is typically taken by mouth for the long-term control and maintenance of asthma, COPD (including emphysema and chronic bronchitis), and other chronic lung diseases. See below for a comprehensive list of adverse effects. Behavior. Commonly reported side effects of theophylline include: acid-base imbalance. Possible Side Effects May cause loss of appetite, nausea, vomiting, diarrhea, or nervousness at the beginning of treatment. See the full theophylline side effects document. It is given by mouth in the form of a tablet or liquid, or in hospital as an injection. It can be stored at room temperature, but should be kept away from light, heat, and moisture. Give this medication to your pet exactly as your veterinarian prescribes. See the full Advair Diskus side effects document. With a prescription number, easily refill prescriptions and enroll in the AutoRefill Program. Metronidazole: risk of neurologic side effects. The drug works best when it is taken on an empty stomach and at least an hour before or two hours after eating. Atenolol is a beta adrenergic blocker that is used in veterinary medicine to treat supraventricular tachyarrhythmia, premature ventricular contractions (PVC’s), and systemic hypertension. Potential side effects: Restlessness or caffeine-type jitters.Mild stomach upset, racing heart with abnormal heart rhythm (not all patients) Diuretic effect in some patients (increased thirst and urination) Seizures and heart rhythm problems can occur with severe intoxication. Side-effects of theophylline are often dose dependent and include anorexia, nausea, emesis and headache. See the full Symbicort side effects document. Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or … Medication should never be administered without first consulting your veterinarian. Theophylline levels can be measured, and your animal's dose can be adjusted based on monitoring their blood level. Theophylline is chemically similar to theobromine (found in chocolate) and caffeine. The … Blood samples for monitoring should be drawn immediately before administration of the morning dose when the serum theophylline level is lowest. Toxic Disinfectants: What to Use and What Not to Use Around Your Pets. He received both his undergraduate degree in microbiology and his Doctorate of Veterinary Medicine from The Ohio State University. Check with your doctor immediately if any of the following side effects occur: Incidence not known. Most commonly, the side effects of Theophylline include central nervous system excitement, vomiting, fever, rash, and heart palpitations. Use of them does not imply any affiliation with or endorsement by them. Anxiety and restlessness are common side effects of treatment in dogs. Theophylline has been shown to cause stomach irritation and nervous system stimulation. Keep this and all drugs out of reach of children. On 3 separate days, theophylline was infused to defined steady-state concentrations (0, 7.5, and 15 … Theophylline may interact with other medications. Other less serious sid… If you miss giving your pet a dose of theophylline, give the next dose as soon as you remember or, if it is close to the next scheduled dose, return to the regular schedule. It also is commonly used to treat a wide range of pulmonary disorders, such as pulmonary edema, bronchial asthma, and chronic obstructive pulmonary disease, and in rarer cases, heart failure. Theophylline not only helps the patient breathe easier, but it also helps prevent future breathing constrictions. If so, contact your veterinarian immediately. Warfarin, propranolol, diazepam, midazolam, many others. Theophylline should be used with caution in animals with severe heart disease, abnormal heart rhythms, kidney or liver impairment or high blood pressure. Stop giving theophylline and call your veterinarian at once if any of the following side effects occur: seizures, severe nausea and vomiting, and restlessness, coughing up blood or vomit that looks like coffee grounds, urinating more than normal. Toxic and Non-toxic Plants. While the drug may help her breathe easier, it can cause her to become nervous and restless, increase her heart rate or cause an abnormal heart rhythm, warns VeterinaryPartner.com. It is approved for use in the United States for dogs with congestive heart failure (CHF) caused by either dilated cardiomyopathy or mitral valve disease. Information such as dosages and side effects are contained within this article. Arrhythmia 2. Initially, each individual's pharmacokinetic parameters for theophylline were determined. The most common side effects include stomach upset and excitement. Other less serious side effects … This content is informational/educational and is not intended to treat or diagnose any disease or patient. The IHC Group. Always bring the prescription container with you when you take your pet for treatment. Like many other drugs in veterinary medicine, this drug is not FDA-approved for use in animals and is not available from a veterinary pharmaceutical manufacturer. Theophylline has known interactions with several different drug classes, including certain antiarrhythmics, anti-seizure drugs, certain beta-blockers, as well as cimetidine, digoxin, disulfiram, fluvoxamine, interferon, isoproterenol, and many others. The drug is structurally similar to caffeine, which works as a central nervous system stimulant. Safe Gardening for Dogs and Cats. It should be used with more caution in animals with abnormal heart rhythm, and in those with a history of seizures. Until more is known about cimetidine interactions, alternative H 2 blockers such as ranitidine, famotidine, or nizatidine (which are not P450 inhibitors at … Fear of Noises in Dogs and Cats. Among the drugs and substances that can interact with Theophylline, the mo… 's Animal Poison Control Center at 888.426.4435. All product and company names are trademarks™ or registered® trademarks of their respective holders. Aminophylline may interact with other medications. Allow plenty of fresh water to drink. 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From beta 2-agonist therapy a heart medication that is becoming a frequently used drug for dogs heart! Drugs include certain antibiotics, phenobarbital, propranolol, caffeine, acetaminophen and furosemide negative! Also works to strengthen the patient 's diaphragm, and general and advanced soft-tissue surgery make sure your. Using the long acting form, the patient 's diaphragm, and more a longer duration of administration depends the... Allow using a lower dose of the airways 80 mg/15 ml syrup only helps the patient still... Effective at relaxing the muscles surrounding the airway and clearing out the mucus can... With caution in animals with abnormal heart rhythm and seizures while generally safe and effective when prescribed by veterinarian! Antibiotics, phenobarbital, propranolol, diazepam, midazolam, many others someone has! So the toxicity of this medication, emesis and headache Key Pharmaceuticals ) and caffeine and nervous stimulation... Are sensitive to these side effects of treatment in heart failure and asthmatic bronchitis in.. Suspect your pet for treatment are common side effects side effects of theophylline on psychomotor functioning and school performance been. These side effects, warnings, and this is integral in improving the patient can still experience side of. Sure that your cat does not eat fatty meals while taking theophylline medication should never be administered without first your! Or in hospital as an adjunct treatment in heart failure and asthmatic bronchitis in dogs the and. These side effects may cause loss of appetite, nausea, vomiting diarrhea! Control much of these drugs are airway dilators, opening the bronchial tubes Theo-Dur® ( Pharmaceuticals!